S.E.M.I.: Side Effects May Include... cover
Log
Want to Play Collection
Loved Add to list

S.E.M.I.: Side Effects May Include... 2026

Two Horn Unicorn · PC

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.

My Save State is where you keep a history of the games you play. Sign up free or sign in

Details

Developers
Two Horn Unicorn
Publishers
Two Horn Unicorn
Genres
Arcade, Hack and slash/Beat 'em up, Indie
Themes
Action, Comedy, Party
See more on IGDB ↗

Released

  1. 2025
    • Nov 20 PC · Early access
  2. 2026
    • Jan 23 PC